Browsing by Author "Ozdemir, Ismail"
Now showing items 1-11 of 11
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Anticancer activities of manganese-based photoactivatable CO-releasing complexes (PhotoCORMs) with benzimidazole derivative ligands
Ustun, Elvan; Ozgur, Aykut; Coskun, Kubra A.; Dusunceli, Serpil Demir; Ozdemir, Ismail; Tutar, Yusuf (SPRINGER, 2017)Carbon monoxide is an important signaling molecule which is produced by heme oxygenase-1. CO shows antiproliferative activity against cancer cells; hence, activation of HO-1 is a significant inhibition strategy against ... -
ARYLATION OF ANILINE AND AMINES BY Pd-(N-HETEROCYCLIC CARBENE) COMPLEXES
Sahin, Neslihan; Dusunceli, Serpil Demir; Ozdemir, Ismail (PERGAMON-ELSEVIER SCIENCE LTD, 2017)Aminoarenes constitute valuable building blocks in organic synthesis and an essential skeleton ubiquitously found in ligands, agrochemicals, and pharmaceuticals. This synopsis presents recent amination methods using ... -
CO-releasing properties and anticancer activities of manganese complexes with imidazole/benzimidazole ligands
Ustun, Elvan; Ozgur, Aykut; Coskun, Kubra A.; Demir, Serpil; Ozdemir, Ismail; Tutar, Yusuf (TAYLOR & FRANCIS LTD, 2016)Carbon monoxide (CO) is an important signaling molecule which plays significant roles in the pathogenesis of cancer. CO is produced by enzymatic degradation of heme in mammals. Heme oxygenase 1 (HO-1) catalyzes the breakdown ... -
Copper-Catalysed Allylic Substitution Using 2,8,14,20-Tetrapentylresorcinarenyl-Substituted Imidazolium Salts
Kaloglu, Murat; Sahin, Neslihan; Semeril, David; Brenner, Eric; Matt, Dominique; Ozdemir, Ismail; Kaya, Cemal; Toupet, Loic (WILEY-V C H VERLAG GMBH, 2015)Unsymmetrical imidazolium salts, each having one nitrogen atom (N1) substituted by a cavity-shaped TPR group (TPR = 2,8,14,20-tetrapentylresorcinaren-5-yl), were tested in situ as proligands for the copper-catalysed allylic ... -
In vivo evaluation of the genotoxic effects of clomiphene citrate on rat reticulocytes: A micronucleus genotoxicity
Duran, Bulent; Ozdemir, Ismail; Demirel, Yeltekin; Ozdemir, Ozturk; Cetin, Ali; Guven, Aysel (KARGER, 2006)Objective: To determine the genotoxic effects of clomiphene citrate (CC) on rat reticulocytes in vivo. Methods: In this prospective, randomized, controlled study, rats were each assigned randomly to the CC 50, CC 100, CC ... -
Resorcinarene-Functionalised Imidazolium Salts as Ligand Precursors for Palladium-Catalysed SuzukiMiyaura Cross-Couplings
Sahin, Neslihan; Semeril, David; Brenner, Eric; Matt, Dominique; Ozdemir, Ismail; Kaya, Cemal; Toupet, Loic (WILEY-V C H VERLAG GMBH, 2013)Three imidazolium salts based on a rigid resorcinarene platform (13) were synthesised and used as catalyst precursors in the SuzukiMiyaura cross-coupling of aryl halides with phenylboronic acid. In these pro-carbene ligands, ... -
Subtle Steric Effects in Nickel-Catalysed Kumada-Tamao-Corriu Cross-Coupling Using Resorcinarenyl-Imidazolium Salts
Sahin, Neslihan; Semeril, David; Brenner, Eric; Matt, Dominique; Ozdemir, Ismail; Kaya, Cemal; Toupet, Loic (WILEY-V C H VERLAG GMBH, 2013)Three resorcinarene-cavitands bearing a 3-R-1-imidazolylium substituent (R = alkyl) grafted to the wider rim of the cavitand (1-3) were assessed in the Kumada-Tamao-Corriu cross-coupling of aryl halides with arylmagnesium ... -
Synthesis and use of trans-dichlorido-tetrakis-(N-R-imidazole)nickel(II) complexes in Kumada-Tamao-Corriu cross-coupling reactions
Sahin, Neslihan; El Moll, Hani; Semeril, David; Matt, Dominique; Ozdemir, Ismail; Kaya, Cemal; Toupet, Loic (PERGAMON-ELSEVIER SCIENCE LTD, 2011)Two dichlorido-tetrakis-(N-R-imidazole)nickel(II) complexes (R = 2,6-diisopropylphenyl (1): methyl (2)) have been synthesised. A single crystal X-ray diffraction study was carried out for 1, which revealed a centrosymmetric ... -
Synthesis, spectral, X-ray diffraction and DFT studies on 1-(2-methyl-2-propenyl)-3-(2,3,4,5,6-pentamethylbenzyl)benzimidazolium chloride hydrate
Sahin, Neslihan; Kilic-Cikla, Isin; Ozdemir, Namik; Gurbuz, Nevin; Ozdemir, Ismail (TAYLOR & FRANCIS LTD, 2018)A new benzimidazole based N-heterocyclic carbene (NHC) salt (1) was synthesized by the reaction of benzimidazole precursor with alkyl halide. The structure of 1 was determined by elemental analysis, FT-IR, H-1 NMR and C-13 ... -
Transfer hydrogenation of ketones catalyzed by 1-alkylbenzimidazole ruthenium(II) complexes
Ozdemir, Ismail; Sahin, Neslihan; Cetinkaya, Bekir (SPRINGER WIEN, 2007)Six [RuCl2(1-alkylbenzimidazole)(p-cymene)] complexes have been prepared and the new compounds characterized by C, H, N analyses, H-1 NMR, and C-13 NMR. The reduction of ketones to alcohols via transfer hydrogenation was ... -
Transfer hydrogenation of ketones in the presence of half sandwich ruthenium (II) complexes bearing imidazoline and benzimidazole ligand
Sahin, Neslihan; Demir, Serpil; Ozdemir, Ismail (ARKAT USA INC, 2015)This article explores the possibility of using imidazoline and benzimidazole derivatives as interesting ligands due to the fact that they are structurally simple, readily available, inexpensive, and they allow easy ...